‘Sure, that is definitely about correct. I seek out a Actual physical understanding of Organic units inside a bottom-up way. I think you may distinguish a few strains of study in my team for the time being. The primary fears chromosome structure: How would you have a metre-long DNA polymer folded and organised in such a microscopic cell? We now have made visualisation techniques that enable us to check how, for instance, SMC proteins loop DNA (video clip on Youtube) so as to Establish up chromosomes.

1996, to start with mesoscopic charge density waves units; and to start with electrical measurements on just one steel nanocluster between nanoelectrodes

‘It was simply a make any difference of finding up a ebook on cell biology and starting to browse. I'd come from a environment of ultra-higher vacuums, cryostats and quantum phenomena, and now I had been Doing work at space temperature with molecular biology kits.

Nanofabrication of electrodes with sub-five nm spacing for transport experiments on one molecules and metal clusters

Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever layout in 2005. (nl)

SMC complexes can pass physical roadblocks larger than their ring sizing, indicating a nontopological system for DNA loop extrusion

We use nanofabricated microfluidic buildings to sample spatial boundaries for micro organism and biomimetic vesicles with reconstituted protein networks which assess the fundamental function of spatial confinement in the molecular and cellular level. Our projects include the subsequent:

Example (one) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is demonstrated in gray, the rim in the pore is highlighted in pink, plus a 3D rendering of the motion of your DNA rod is displayed.

The rotors harness energy from the nanoscale drinking water and ion flow that may ceesdekker.net be produced by a static chemical or electrochemical possible gradient in the nanopore, which happen to be proven through a salt gradient or used voltage, respectively. These artificial nanoengines self-Manage and function autonomously in physiological conditions, suggesting tips on how to setting up energy-transducing motors at nanoscale interfaces.

Bulk-surface area coupling identifies the mechanistic link involving Min-protein styles in vivo As well as in vitro

[14] In 2005 Dekker grew to become involved in Netherlands-extensive conversations about Intelligent Style and design, a movement that he has considering the fact that Obviously distanced himself from. Dekker advocates that science and faith are not in opposition but might be harmonized.

Nanoscientist Cees Dekker can be an amiable and flamboyant person who seems Significantly younger compared to the sixty two yrs he in fact is – trendy glasses, psychedelic shirt, partaking smile – but not one to squander time. He normally takes his time, but no more than necessary.

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2013, controlled shaping of live bacterial cells into arbitrary designs; and discovery of spontaneous fluctuations in the handedness of histone tetrasomes